Start Submission Become a Reviewer

Reading: Virilization in a postmenopausal woman: ovarian steroid cell tumour

Download

A- A+
dyslexia friendly

Case Reports

Virilization in a postmenopausal woman: ovarian steroid cell tumour

Authors:

S Pathmanathan ,

Senior Registrar, Endocrinology, National Hospital of Sri Lanka, LK
X close

Noel P Somasundaram,

Consultant Endocrinologist, National Hospital of Sri Lanka, LK
X close

N Wijewardena,

Consultant Interventional Radiologist, National Hospital of Sri Lanka, LK
X close

HR Senevirathne,

Professor of Obstetrics and Gynaecology, University of Colombo, LK
X close

D Lokuhetty

Professor of Pathology, Faculty of Medicine, University of Colombo, LK
X close

Abstract

Rapid onset of virilization in a post-menopausal woman is usually the result of androgen secretion from a tumour of adrenal or ovarian origin. Androgen secreting neoplasms of the ovary are rare and usually show autonomous secretion. We describe the case of a 61-year-old woman with high serum testosterone and inappropriate normal estrogen despite menopause. Localization of the tumour was not possible by conventional ultrasound or computerized tomography scanning, and was achieved by venous sampling. Complete cure was achieved by oophorectomy. Histopathological examination confirmed the diagnosis. Postoperatively her testosterone returned to normal. Two months after surgery she showed regression of features of hyperandrogenism.

DOI: http://dx.doi.org/10.4038/sjdem.v1i1.4189  

Sri Lanka Journal of Diabetes Endocrinology and Metabolism 2011; 1: 37-40

Keywords: post-menopause 
How to Cite: Pathmanathan, S. et al., (2012). Virilization in a postmenopausal woman: ovarian steroid cell tumour. Sri Lanka Journal of Diabetes Endocrinology and Metabolism. 1(1), pp.37–40. DOI: http://doi.org/10.4038/sjdem.v1i1.4189
Published on 25 Mar 2012.
Peer Reviewed

Downloads

  • PDF (EN)

    comments powered by Disqus