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Endocrine late effects in paediatric cancer survivors

Authors:

Sumudu Nimali Seneviratne ,

Senior Registrar in Paediatric Endocrinology and Lecturer, Faculty of Medicine, University of Colombo, LK
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KSH de Silva

Professor in Paediatrics, Department of Paediatrics, Faculty of Medicine, University of Colombo, LK
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Abstract

CORRECTION: The author of this paper was changed from Bimalka Seneviratne to Sumudu Nimali Seneviratne and KSH de Silva on 13/05/2013.

Improved survival following childhood malignancy has led to increased recognition of a multitude of late adverse effects in long term survivors, which affect their quality of life. Endocrine complications are among the commonest late effects seen and include dysfunction of the hypothalamo pituitary axis leading to impaired growth, abnormal puberty or hypopituitarism, gonadal dysfunction and infertility, thyroid gland dysfunction and neoplasms, obesity, impaired glucose homeostasis and abnormal bone development. Long term follow up is needed for early recognition and timely intervention to minimise the effects of these complications.

Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2012; 2: 89-91

DOI: http://dx.doi.org/10.4038/sjdem.v2i2.4778

How to Cite: Seneviratne, S.N. & de Silva, K., (2012). Endocrine late effects in paediatric cancer survivors. Sri Lanka Journal of Diabetes Endocrinology and Metabolism. 2(2), pp.89–91. DOI: http://doi.org/10.4038/sjdem.v2i2.4778
Published on 18 Oct 2012.
Peer Reviewed

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