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Investigating for the aetiology of Cushing’s syndrome: where we can go wrong

Authors:

MI Weerakkody ,

Endocrine and Diabetes Unit, National Hospital of Sri Lanka,Colombo, LK
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P Katulanda,

Department of Clinical Medicine, Faculty of Medicine, Colombo, LK
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S Perera

The Central Hospital, Colombo, LK
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Abstract

The diagnosis of Cushing’s syndrome as well as delineating its aetiology can be often challenging, especially in the mild cases with atypical features. Although the combined clinical features such as the age, gender and the severity of the hypercortisolism can usually help to differentiate between pituitary ACTH hyper secretion from an ectopic ACTH source, this may sometimes be inaccurate. The presence of caveats in most biochemical testing and imaging modalities as well as the relative unavailability of certain dynamic tests and catheter based studies can contribute to the dilemma.

Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2012; 2: 114-117

DOI: http://dx.doi.org/10.4038/sjdem.v2i2.4783
How to Cite: Weerakkody, M., Katulanda, P. & Perera, S., (2012). Investigating for the aetiology of Cushing’s syndrome: where we can go wrong. Sri Lanka Journal of Diabetes Endocrinology and Metabolism. 2(2), pp.114–117. DOI: http://doi.org/10.4038/sjdem.v2i2.4783
Published on 18 Oct 2012.
Peer Reviewed

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