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Brief Research Communications

Prevalence of thyroid dysfunction among type 2 diabetic patients attending the Diabetes Clinic, National Hospital of Sri Lanka

Authors:

Shyaminda Kahandawa ,

National Hospital of Sri Lanka, LK
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Noel P Somasundaram,

National Hospital of Sri Lanka, LK
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Dileepa S Ediriweera,

University of Kelaniya, LK
About Dileepa S
ICT Resource Centre, Faculty of Medicine
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DP Kusumsiri,

National Hospital of Sri Lanka, LK
About DP
Diabetic Clinic
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S Ellawala,

National Hospital of Sri Lanka, LK
About S
Diabetic Clinic
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GHTNK Chandrika,

National Hospital of Sri Lanka, LK
About GHTNK
Diabetic Clinic
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KGH Ransarini

National Hospital of Sri Lanka, LK
About KGH
Diabetic Clinic
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Abstract

Objective: To determine the prevalence of thyroid dysfunction (TD) and to identify risk factors which are associated with TD in Type 2 Diabetic (T2DM) patients attending the Diabetes Clinic, National Hospital of Sri Lanka

Method: A descriptive cross sectional study was carried out at the Diabetes Clinic, National Hospital of Sri Lanka. Study subjects were selected by simple random sampling method and data was collected using an interviewer administered data collection form. TD was assessed by performing 3rd generation TSH and when required FT4/FT3 levels were measured. Statistical analysis was done using Pearson’s Chi-square test, Fisher exact test, Mann Whitney U test and Wilcoxon Rank Sum test and P value < 0.05 was considered as significant.

Results: TD was detected in 83 out of 393 T2DM subjects.The prevalence of TD among study subjects was 21.1% (95% CI:17.2-25.5%). The most common TD categories were subclinical hypothyroidism (9.4%, 95% CI:6.7-12.7%) and overt hypothyroidism (6.1%, 95% CI:3.9-8.9%). Subclinical hyperthyroidism and overt hyperthyroidism were detected only in 5.1% (95% CI:3.1-7.8%) and 0.5% (95% CI:0.1-1.8%) of cases respectively. The presence of TD was strongly associated with female sex (p<0.01) advancing age (p<0.01),the presence of goitre (p< 0.01) and a positive family history of thyroid disorder among 1st degree relatives (p=0.02).There was no association between the presence of TD and the duration of T2DM, presence of hypertension or chronic complications of DM, type of antidiabetic drugs used, current glycaemic control, body mass index (BMI) and total cholesterol level.

Conclusion: The prevalence of TD was 21.1% and higher prevalence was seen in T2DM patients with female sex, advancing age, presence of goitre and positive family history of thyroid disorder among 1st degree relatives.  

DOI: http://dx.doi.org/10.4038/sjdem.v4i1.7254

Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2014; 4: 43-48

How to Cite: Kahandawa, S. et al., (2014). Prevalence of thyroid dysfunction among type 2 diabetic patients attending the Diabetes Clinic, National Hospital of Sri Lanka. Sri Lanka Journal of Diabetes Endocrinology and Metabolism. 4(1), pp.43–48. DOI: http://doi.org/10.4038/sjdem.v4i1.7254
Published on 05 Aug 2014.
Peer Reviewed

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