Authors:

Abstract

Objectives: Pre-diabetes is almost always a precursor to the development of type 2 diabetes. Comparison of EZSCAN with existing screening methods for detection of pre-diabetes and diabetes was done.

Settings and Design: Cross sectional epidemiological study.

Material and Methods: All cases underwent the EZSCAN test and had fasting plasma glucose (FBG), post-prandial plasma glucose (PPBG) and HbA1c level estimation. The results of EZSCAN were compared with fasting blood glucose, post-prandial blood glucose and HbA1c levels.

Statistical analysis used: Mean, Standard deviation, sensitivity, specificity, positive and negative predictive value.

Results: The sensitivity and specificity of EZSCAN when compared with FBG in diabetes was 87.2% and 87.2% respectively, for pre-diabetes 80.4% and 74.3% respectively and for non-diabetes 51.1% and 97.8% respectively. The sensitivity and specificity of EZSCAN when compared with PPBG in diabetes was 86.5% and 85.2% respectively, for pre-diabetes 76.9% and 72.6% respectively and for non-diabetes 52.8% and 98.9% respectively. The sensitivity and specificity of EZSCAN when compared with HbA1c in diabetes was 86% and 90.2% respectively, for pre-diabetes 87.8% and 71.4% respectively and for nondiabetes 46.3% and 98.8% respectively.

Conclusions: EZSCAN proved to be a sensitive, specific, easy to perform screening test for diabetes and pre-diabetes which can be performed in non fasting state. EZSCAN is a simple device that can be operated by non medical personnel in non-healthcare settings with minimal subject preparation.

Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2015; 5: 4-7

Keywords: EZSCAN, diabetes, pre-diabetes